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Monday, 10.08.2020, 19:02
Main » Pediatrics » Bleeding diathesis 
16:07
Bleeding diathesis


Bleeding diathesis

Chronic idiopathic platelet purpora - the most common form in children hemorrhagic diathesis due to a significant decrease in platelet count and reduced resistance of the capillaries.


The most common form of chronic idiopathic immune platelet purpory. Under the influence of various endo-and exogenous factors antiplatelet antibodies are formed, is fixed on the surface of platelets and cause their destruction increased. Characterized by asymmetrically located polymorphic hemorrhages from small petechiae to extensive subcutaneous hemorrhage occurring spontaneously or under the influence of the slightest injury, bleeding from the mucous membranes of the mouth, nose, gastrointestinal tract, and sometimes lung, kidney, and uterine bleeding. The spleen is usually not enlarged.

The main feature gemotologichesky - thrombocytopenia. Sometimes a mild leukocytosis, neutrophilia. Red blood parameters depend on the degree of blood loss. Duration of bleeding is increased. Coagulation time was normal.

Diagnosis is based on characteristic clinical symptoms, thrombocytopenia, prolongation of bleeding time. Relatively favorable prognosis. With age, the tendency to bleeding is reduced. Mortal danger may be profuse bleeding and bleeding into vital organs.

Treatment of Bleeding diathesis:

Assign Dicynone, ascorbic acid and 1 g per day, vitamin E, corticosteroid hormones (prednisone 1-2 mg \ kg) for 1.5-2 months. Hemostatic measures in hemorrhages: transfusion of fresh plasma, trombotsitnoy suspension.


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