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Monday, 25.09.2023, 17:02
Main » Pediatrics » Hermaphroditism 


Androgyny is accompanied by anomalous (bisexual), the structure of the external genitalia.

anomaly structure of the external genitalia in patients with a woman's genetic sex (karyotype 46 XX) is denoted by the term "false female hermaphroditism"

abnormalities in patients with male genetic sex (XY karyotype 46) - "false male hermaphroditism"

the exception of a rare form - true hermaphroditism, in which there may be a 46 XY karyotype, 46 XX or 46 XY \ 46 XX.

External genitalia are bisexual structure with varying degrees of virilization. Internal genitalia, usually have feminine traits: a womb (often horned), the vagina, pipes. At puberty in patients who tend to dominate feminine traits.

Diagnosis of hermaphroditism

To begin screening children should primarily determine the sex chromatin and karyotype. Identification of a positive sexual chromatin and karyotype 46 XX more likely to indicate a false female hermaphroditism.

Accurate diagnosis can be made only during laparotomy, the macroscopic and histological examination of gonads. In the case of a negative sexual chromatin should be a differential diagnosis between the various forms of false male hermaphroditism.

The presence of uterine tubes and vagina with the karyotype 46 XY and 46 XY mosaic \ 45 X0 suggests the presence of testicular dysgenesis syndrome. Much less can be detected with a bisexual gonadal (true hermaphroditism). If the karyotype 46 XY, and the absence of the uterus and upper third of the vagina should think about the syndrome of incomplete virilization.

A significant difficulty is the differential diagnosis between partial and incomplete masculinization of the form form of testicular feminization. The difference is detected only at puberty, when children with an incomplete form of testicular feminization spontaneously begin to develop breasts, develops the figure of the female type, and incomplete masculinization syndrome observed all the signs of male puberty.

Treatment Hermaphroditism

In all forms of false hermaphroditism female female choice is clear. Of congenital dysfunction of the adrenal cortex, adequate and timely initiated therapy with cortisone to avoid further vilirezatsii, creates conditions for further physiological formation of ovarian cancer.

When the wrong man hermaphroditism at a satisfactory development of the corpora cavernosa of the penis is selected male and produce maskuliniziruyuschuyu plastic genitalia.

In true hermaphroditism is desirable choice of female gender. Produce feminizing plastic genitalia.

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