Atopic dermatitis - an allergic skin disease based on having a predominantly Ig E - mediated mechanism of development. This disease is registered in 1-3% of children. Atopic dermatitis is a hereditary itchy dermatoses. Due to a genetic predisposition to allergic skin reactions.
In the pathogenesis of atopic dermatitis play a pivotal role to functional immune deficiency, disorder of the nervous system and psycho-emotional sphere are rather secondary. Atipchesky dermatitis usually makes its debut in early childhood, usually during the second half of life. The disease can last for many years, and is characterized by remissions mostly in summer and autumn periods of relapse in the year.
In the course of the disease are three phases:
infant (up to three years)
children (3-7 years)
The first signs of atopic dermatitis in a light red skin, scales on the eyebrows and scalp emerge from the early stages. Subsequently, there are erythema and edema of the skin, in this background, there are small bubbles, which are formed during drying of thick brown crust.
Manifestations of cutaneous manifestations of atopic dermatitis is accompanied by itching of the skin lesions which often appear scratches. The subsequent development of atopic dermatitis may lead to the following forms:
eczematous (occurs in 3-5 months. life is characterized by small blisters with serous content and intense itching)
lichenoid (from 7-8 months. life, characterized by the appearance of dense knots of pale-papules, covered with scales on the background of pityriasis edematous and erythematous skin)
pruriginoznoy (in children older than 5 years, is characterized by genital or spherical nodules - papules that are at the top of the bubble).
During atopic dermatitis accompanied by an increase in peripheral lymph nodes, in addition there are violations of the digestive system. In 30% of sick children celebrated the accession of respiratoronoy allergies. In children with atopic dermatitis observed increased irritability, sleep disturbance, fatigue.