Diffuse toxic goiter - the most common thyroid disease in childhood. Is a genetically determined autoimmune disease. The most frequently ill children 11-15 years old, get sick more often girls. The main complaints are irritability general weakness and fatigue on exertion say sometimes heartbeat, weight loss accompanied by increased appetite, increased sweating, frequent headaches, memory loss and deterioration of academic achievement in children at school. More gradual onset, but in some cases can rapidly develop a severe form.
Clinic diffuse toxic goiter in children has some peculiarities: even under very severe very rarely develop heart failure, rapid growth in the period of the disease, delay of sexual development. Patients are usually asthenic physique, tall. Skin velvety soft and moist. Note the red-resistant dermographism, eyelids, elbows. Patients who develop muscle weakness.
The thyroid gland is diffusely enlarged, which is one of the major symptoms of diffuse toxic goiter.
Violation of the cardiovascular system in diffuse toxic goiter may be so severe and leading to the clinic that initially thyrotoxicosis regard as heart disease. There have been marked tachycardia, even at rest, increased pulse pressure, which leads to a marked pulsation of large vessels, increased heart tones. Degree corresponds to the severity of tachycardia diffuse toxic goiter. The ECG sinus tachycardia and fibrillation high voltage teeth violation predserdnozheludochkovoy conductivity. It is also common ocular symptoms.
Characterized by disturbances in the motor area. Note the tremor of the fingers outstretched hands of closed eyelids, and tongue, while severe forms - whole-body vibration (a symptom of "telegraphic" column)
When diffuse toxic goiter observed in a number of disorders of the endocrine glands. There is a deviation in the process of sexual maturation: a later development of secondary sexual characteristics and the onset of menarche, menstrual function. In the clinical analysis of blood noted a tendency to leukopenia and lymphocytosis.
The main criterion is to increase tireotokzikoza iT4 T3 in serum with normal or reduced TSH.
Treatment of diffuse toxic goiter in children and conservative surgery.
