So far, no unified theory of the causes of peptic ulcer disease. Distinguish between primary and predisposing factors that lead to peptic ulcer disease.
The main factors of peptic ulcer:
disorder of the nervous and hormonal mechanisms regulating functions of the stomach
Local digestive disorders and trophic changes in the gastro-duodenal system - a violation of the protective mechanisms of the mucous membrane of the stomach and duodenum (duodenal)
disturbances of local blood circulation and innervation
the presence of bacteria.
Predisposing factors of peptic ulcer:
bad habits, etc.
In children, peptic ulcer disease occurs quite often. Basically there is duodenal ulcer, gastric ulcer less.
The leading symptoms of duodenal ulcer are pain on an empty stomach - the hungry, sometimes at night, subsiding after a meal. There may be pain-free start, atypical course, rapid progression, resulting in late diagnosis and treatment.
When gastric ulcer pain usually occur shortly after eating, pain localized in the epigastric region; young children around the navel or spills around the abdomen. Vomiting is a second important symptom. There is usually at a height of exacerbation. Heartburn and regurgitation are detected less frequently. Frequent constipation. Characterized by seasonal exacerbations - spring autumn. During the period of acute illness marked symptoms of intoxication.
deformation or stenosis of the pylorus or piloroduodenalnoy area
Massive bleeding in children are less common. Usually accompanied by bloody vomiting or tarry stools, increasing weakness, a sharp decrease in hemoglobin level. More likely to be hidden bleeding, detected in the analysis of fecal occult blood. For a rough strain with pyloric stenosis or region is characterized by abundant piloroduodenalnoy vomiting food to the preceding nausea, acid regurgitation, weight loss, appetite, visible peristalsis of stomach. Perforation usually develops acutely.