Is an undeniable fact that current trends in the treatment of endocrine diseases transplanted cells and tissues has a place. Become a real chance of success in treating patients once doomed.
Of great importance, transplant hormonally active cells or fragments of any of the endocrine glands to restore lost function.
The fact that continuous hormone replacement therapy puts its stamp on all organs and systems, leading to disruption of metabolism, various physiological disorders. In this case, the graft is able to restore and maintain normal levels of hormones in the blood, while not inhibiting the endocrine glands. For correction of endocrine disorders can be transplanted individual cells or parts of gormonprodutsiruyuschih cancer.
In recent years, one of the options for replacement therapy in endocrine pathology can be considered as cell transplantation.
Conducted experimental and clinical studies on the transplantation of adrenal gland, ovary, parathyroid, thyroid, pancreas glands. Best results are achieved with transplantation of pancreatic cells. During the procedure, the patient with diabetes first type of transplanted insulin-producing cells. Due to the fact that only the transplanted cells in the pancreas, surgery is low-impact nature. Under ultrasound catheter was installed in the portal vein of the liver, through which, later, entered the cell. The graft is retained in the liver, where it begins to actively supplied with blood, and responds to fluctuations in blood glucose levels, while releasing enough insulin. The response to these changes appear almost immediately and in the first few weeks of their function improves.
Transplantation of cells and tissues of the endocrine glands and the problem of acute rejection. Hyperacute rejection does not occur so often, because there is no vascular reunion between donor organ and recipient. But there remains the likelihood of acute rejection. Trigger this reaction is the process of recognition of the graft as foreign material.
An important component of post-operative treatment is the appointment of special combinations of immunosuppressive drugs. Patients who underwent transplantation of pancreatic islet cells should be in the rest of their lives to get this treatment to prevent rejection of transplanted cells.