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Friday, 14.12.2018, 18:53
Main » Pediatrics » hypogonadism Treatment 
16:59
hypogonadism Treatment


hypogonadism Treatment

Hypogonadism - a lack of secondary sexual characteristics in boys older than 13 years showed a lack of function of the gonads. The reasons are related to either damage to the reproductive glands themselves (primary hypogonadism) or organic damage regulating sexual function of the hypothalamic-pituitary structures (secondary hypogonadism).


Hypogonadism is divided into:
  • gipergonadotropny (primary) - congenital and acquired
  • hypogonadotropic (secondary) - congenital syndrome (Kallmann syndrome, Laurence-
  • Moon-Bardet-Biddle, Prader-Willi syndrome)
  • acquired - delayed puberty - constitutional, somatic, hormonal imbalance.


A frequent cause of hypothyroidism is functional gonads delay maturation of the central mechanisms responsible for sexual development of genetic or somatic (somatic constitutionally-delayed puberty).

Lack of effect of androgens on bone and muscle tissue leads to the formation evnuhoidnyh proportions: elongation of limbs, high waist, excessive deposition on the hips. There is no age heterophonia, muscles flabby and weak. Infantile external genitalia, testes size matches dopubertatnomu, testicular consistency or loose or tight.

In some cases, noted the development of gynecomastia. An example is the syndrome of Laurence-Moon-Bardet-Biddle, accompanied by significant obesity, mental retardation, syndactyly, retinitis pigmentosa.

Klinefelter syndrome is characterized for the tall, mental retardation, gynecomastia.

Violation of smell - a characteristic symptom of the syndrome Kalman.

Treatment of hypogonadism

Treatment of primary hypogonadism - replacement therapy male sex hormones.

For the treatment of secondary hypogonadism using drugs horeonicheskogo gonadotropin.

When constitutional delay of puberty specific treatment usually do not spend



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